ORENCIA (Abatacept)

ORENCIA (Abatacept)

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Description

What Is Orencia?

Orencia (abatacept) is a recombinant DNA generated fusion protein used to treat the symptoms of rheumatoid arthritis and to prevent joint damage caused by these conditions. Orencia is also used to treat arthritis in children who are at least 6 years old. Orencia is not a cure for any autoimmune disorder and only treats symptoms.

What Are Side Effects of Orencia?

Common side effects of Orencia include:

  • headache,
  • nausea,
  • diarrhea,
  • stomach pain,
  • indigestion,
  • dizziness,
  • flushing,
  • back pain, or
  • cold symptoms such as stuffy head/nose, sneezing, sore throat, or cough.

Serious side effects of Orencia include:

  • fever,
  • chills,
  • night sweats,
  • flu symptoms,
  • weight loss,
  • feeling very tired,
  • fatal infections,
  • shortness of breath,
  • changes in the amount of urine,
  • pain when urinating, and
  • severe abdominal pain.

Dosage for Orencia

Orencia is supplied in single use vials at a strength of 250mg per vial. Orencia is administered intravenously (IV) as a 30-minute infusion. Dosing is based on the patient’s weight. Following the initial intravenous administration, an IV infusion is given at 2 and 4 weeks after the first infusion and every 4 weeks thereafter.

What Drugs, Substances, or Supplements Interact with Orencia?

There may be other drugs that can interact with Orencia. The prescribing doctor needs to know all medications (including herbals) that the person is taking.

Orencia During Pregnancy and Breastfeeding

During pregnancy, Orencia should be used only when prescribed. It is unknown if Orencia passes into breast milk or if it would harm a nursing baby. Breastfeeding is not recommended while using this drug.

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