Same Quality as brand-name
All drugs (brand-name and generic) are reviewed and authorized for sale by Health Canada before they are available for prescription.
Generic medicines work the same way in the body as the original brand-name drug.
Generic Medicine Contain Same Active Ingredients as brand-name
Generic medicine drugs have the same active ingredient (the chemical that makes the drug work) to work the same way in the body as the brand-name drug. Generic drugs must also have the same amount of active ingredient in the prescription.
The non-medicinal ingredients, such as fillers and preservatives on the generic medicine may be different from the brand-name product, but they are also regulated and subject to the same review process.
Same Manufacturing Standards as brand-name
To receive a license to manufacture and sell drugs in Canada, both brand-name companies and generic medicine drug companies must follow the same Good Manufacturing Practices (GMP) guidelines, which ensure consistent production and quality standards.
The standards for bioequivalence in Canada are built upon internationally recognized standards and the criteria are amongst the highest in the world. Health Canada scientists ensure that the standards for bioequivalence are adhered to and kept up to date as they work closely with an expert panel of scientists, physicians, and pharmacists from across the country.
Bioavailability is a measure of the rate and extent to which the therapeutically active ingredient in a drug product is absorbed into the body. Bioavailability is assessed using two main variables: blood concentration over time; and, the maximum concentration of the active ingredient in the blood stream.
If two different drug products provide the same bioavailability, then they are bioequivalent. If a generic medicine is bioequivalent to the brand-name version, there is no meaningful difference between them in terms of the drug’s safety and the way in which the drug works in the body. A bioequivalent generic medicine or drug is as safe and as effective as the brand-name version.
In a typical bioequivalence study, there are between 32 and 72 people tested. These individuals are separated into 2 groups and the study includes two periods.
In the first stage, Group 1 is given a generic drug and Group 2 is given the brand-name version of the drug. The extent of drug absorption based on the blood concentration of the drug over time, the maximum observed concentration of the drug and the time it takes to reach that maximum concentration are measured to assess the bioavailability of the drug in both groups of peoples.
At the second stage of the bioequivalence study, the group that received the generic medicine or drug in stage one is now given the brand-name drug, and the group that was given the brand-name drug is given the generic drug. The bioavailability of the drug in these two groups is assessed and measured in the same way as stage one. The bioavailability of the brand-name drug is then compared to that of the generic medicine in each individual participating in the study. When these comparisons demonstrate a similar extent of absorption and a similar maximum drug concentration, bioequivalence is proven and the generic drug is confirmed to be as safe and effective as the brand-name version.
Scientifically Acceptable Variability – Every individual’s absorption and the maximum concentration achieved are unique; no one absorbs at the same rate as another person, and no single individual will absorb the exact same amount of the active ingredient at various times after drug administration, therefore health authorities have developed something called an “acceptable range of variability.” When testing a drug across a large number of people to determine a drug’s safety and effectiveness, variability must be part of the analysis because even though the drug is the same, everyone’s response will not be the same. This “acceptable range of variability” exists when testing a brand-name drug as well as when testing generic drugs.
Generic medicine are copies of brand name drugs or medicine that are made and sold after the original patent expires.
Save Up To 80% Off Medications?
Several drugs, in particular, have become very common – a key example of this is kamarga, a generic medicine used to treat erectile dysfunction. It costs are much more affordable then other drugs. The active ingredient of Kamarga is sildenafil. Viagra, a popular brand-name drug, used for the same purpose, also uses sildenafil as its active ingredient. The difference lies in price, with the latter costing $60 – over 12 times kamarga’s cost. At RxDrugsCanada.com you purchase it at less the half the price.
Other drugs used to treat erectile dysfunction or impotence is Generic Cialis that has tadalafil as its active ingredient and costs under $2. On the other hand, its brand-name version, Cialis, costs about $30 a dose – 15 times greater than tadarise, despite having the same active ingredient and you can buy this generic medicine online at substantial lower costs at RxDrugsCanada.com
Finpecia, a generic medicine used to address male pattern baldness, can be purchased for much cheaper at RxDrugsCanada.com but brand-name versions like, Proscar and Propecia, cost much more and you can buy the Generic Version at RxDrugsCanada.com much more less. Again, they share the same active ingredient, finasteride. So why waste money on the brand name drugs that only empty your pockets.
People suffer from extreme sleepiness or drowsiness as a result of narcolepsy or other sleep disorders can manage their conditions using many different kinds of medication at substantially lower prices.
Using even the highest price for the generic, the brand-name one costs over 13 times more at your local pharmacy comparing with generic drugs or generic medicine.
Of course, the prices above may vary, depending on where they are purchased, the buyer’s insurance, the strength of the medication; the volume of pills purchased; but, regardless, there is a very significant difference between the prices of the generic medicine and brand-name versions, over ten times in all the examples discussed above. Given these price differentials, it is worth analyzing how generic and brand-name drugs are the same and what the circumstances are that prompt manufacturers to price the drugs so differently.
One of the most critical points is that generic medicine contain the same active ingredients as brand-name medicine in equal amounts, are meant to address the same conditions in the same way, and even have the same side effects. Their producers are held to the same manufacturing standards as those producing brand-name drugs. However, generic drugs may be packaged or marketed differently from their name-brand versions; they may also have differences in taste, color or some trace ingredients. In effect, though, they must be essentially the same drug.
The drug manufacturers’ ability to price generics lower relies on the brand-name manufacturers initially owned patent. The patent, usually lasting about 20 years, gives owners exclusive ability to produce, sell, and, most importantly, generate more profit from these drugs.
In practice, this translates to a monopoly – or something very close to it – for the owners of these patents, allowing them to recoup their investments several times over. This is especially true for life-saving drugs, for which there are no alternatives on the market, and those struggling with the conditions are likely to exhaust all means possible to purchase the drugs, however expensive they may be.
Once the patents expire, however, generics manufacturers are able to produce and sell the drugs and you can get the best price on your medications at RxDrugsCanada.com, but at much lower prices because they did not have to invest billions of dollars during the research and development phase. The entrance of competitors also effectively breaks the monopoly discussed above, naturally placing downward pressure on the pricing of all manufacturers. Of course, generics manufacturers are rigorously screened by the US Food and Drug Administration, and other similar regulatory bodies around the world, to ensure that generic drugs are just as safe and effective as their brand-name counterpart.
Over the years, generic drugs have become increasingly widespread, in no large part due to their dramatically lower cost. In the United States, a reported 88% of all prescriptions are for generic drugs; it is estimated that the US health-care system saved $254 billion through the use of generic drugs (as opposed to their brand-name versions).
A company like RxDrugsCanada.com can procure a generic medicine at an affordable price and save you over 80% on your medications, and best of all their motto is nobody beats their prices.
Nonetheless, there are still reports of medical professionals supposedly counseling their patients to purchase generic-name versions at significant savings. These are, in turn, attributed mainly to pressure, or incentives, from pharmaceuticals producing brand-name drugs that want to continue to keep their hold over captive markets. However, it is also true that RxDrugsCanada.com require you to obtain a prescription from your doctor. If you require medication your prescriptions for generic versions of the brand-name drugs if requested by you from your doctor is very simple. Online reputable pharmacies like RxDrugsCanada.com are also likely to procure drugs at the best prices from a regulated pharmacy in the country of origin long as these are permitted by national laws and international regulatory bodies saving you a lot of money on your prescription medication.
The initial investment required for the research and development process for the drugs is often cited as the primary reason to allow brand-name manufacturers to sell their drugs at such high prices. Hence, governments and regulatory bodies are often caught between making medicines as easily accessible as possible and protecting the profit-making capacities of pharmaceuticals to ensure that they continue their research and development efforts to improve the drug regimes for various diseases.
Generic or Brand Medicine?
So the question now is, if your doctor or pharmacist offers you a generic medicine of your current medication, should you take it? The short answer in most cases is, yes.
“Brand-name medications are not always better. Many of them are highly expensive,” says Dr. Niteesh K. Choudhry, professor of medicine at Harvard Medical School and executive director of the Center for Healthcare Delivery Sciences at Brigham and Women’s Hospital. As a result of this high cost, some people may skip doses or not take a drug at all because they just can’t afford it. In this way, generics may be a clear winner. In many states pharmacists are required to provide you with the generic version of the medication, unless your doctor specifies otherwise.
It’s estimated that if more prescribers substituted generic medicine for brand-name drugs, drug spending could drop substantially, as much as $5.9 billion by some estimates, says Dr. Choudhry. In addition, there is really no hard proof at this point that generic medications are any less effective or safe than the originals. These drugs are heavily regulated, which can give you some assurances about quality.
While researchers will likely continue to look into the performance of generic medicine versus brand-name drugs, the bulk of research out there shows that taking the no-name brand not only saves you money, but also provides you with a medication that is just as effective as the original.
That said, if you do switch to a generic version of your medication and notice new or worrying symptoms, it’s definitely something to bring up with your doctor.